![]() Hanna noted: “Since we know what it takes to support the growth of outside the uterus (device and conditions), we can finally test whether and which stem cells can generate an embryo ab initio only from stem cells.” The system they developed uses bottles filled with liquids that act as a culture for the cells, which can rotate or remain static at different points of development. Hanna’s team had already published details of one particularly important part of the puzzle last year in Nature, when they outlined the process they had used to grow embryo models outside of a uterus. This is the latest step in a long line of incremental steps in recent years to create an embryo from scratch in the lab. Jacob Hanna’s laboratory at the Weizmann Institute of Science in Rehovot, Israel. However, being able to build them from scratch helps researchers bypass potentially expensive and unethical experiments on embryos and also helps them verify if assumptions about how they work are correct.Ī paper recently published in Cell outlines the achievement by researchers in Prof. Research on both mice and human embryos can offer insight into the mechanisms that allow them to divide, implant, and develop. This suggests that these models were similar enough to natural embryos that they could be studied to gain insight into how they work. Genetic analysis revealed that the structures and cell activity in these embryo models were 95% similar to real mouse embryos and functional. This month, researchers announced that they have been culturing a mouse embryo model made entirely out of embryonic stem cells and without the use of a sperm and egg, or a uterus, for 8.5 days, about 2 days longer than previous experiments had achieved. Share on Pinterest Why are scientists creating ’embryos’ without sperm or eggs? Image credit: Science Photo Library – ZEPHYR/Getty Images.
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